Bis(pentafluorophenyl)xenon is an unstable organic compound of xenon. It consists of two fluorinated phenyl rings connected to xenon.

Bis(pentafluorophenyl)xenon is a molecular substance. In the solid form it crystallises in the monoclinic system with space group P21/n. The unit cell has four molecules with a = 13.635 A. b = 8.248 A. c = 11.511 A, b = 102.624°. The unit cell volume is 1263.18 A3.

The molecules have carbon to xenon to carbon bonds in nearly a straight line (the bond angle is at least 175°). The carbon-xenon bond lengths are 2.35 and 2.39 A. The two pentafluorophenyl rings are twisted by 72° with respect to each other.

Bis(pentafluorophenyl)xenon decomposes above −20 °C and can explode.

Xe(C6F5)2 is prepared from the [(CH3)4N]F catalyzed reactions of (CH3)3SiC6F5 and XeF2 in propionitrile, propionitrile/acetonitrile, acetonitrile, or CH2Cl2 , at -60 to -40 °C as the first [10-Xe-2] species with two xenon-carbon bonds as a colorless solid that decomposes above −20 °C and spontaneously at 20 °C. C6F5XeF is formed  as an intermediate which has been characterized by NMR spectroscopy.

Xe(C6F5)2 is also formed from the reaction of C6F5XeF with Cd(C6F5)2

However, the direct introduction of the C6F5 group into XeF2 with Cd(C6F5)2 is not successful.

Bis(pentafluorophenyl)xenon is crystallized from dichloromethane at −40 °C.

Bis(pentafluorophenyl)xenon reacts with mercury to make bis(pentafluorophenyl)mercury.

Bis(pentafluorophenyl)xenon reacts with hydrogen fluoride to form pentafluorophenyl xenon fluoride C6F5XeF.
In acetonitrile solution bis(pentafluorophenyl)xenon decomposes to form C6F5-C6F5 (C12F10) and xenon. But in dichloromethane solution the product is mostly pentafluorobenzene.

It reacts with iodine to make pentafluoroiodobenzene (C6F5I).