2W2J
770
12348
ENSG00000063180
ENSMUSG00000003273
O75493
O70354
NM_001217
NM_009800NM_001368349
NP_001208
NP_033930NP_001355278
Carbonic anhydrase-related protein 11 is a protein that in humans is encoded by the CA11 gene.
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA XI is likely a secreted protein, however, radical changes at active site residues completely conserved in CA isozymes with catalytic activity, make it unlikely that it has carbonic anhydrase activity. It shares properties in common with two other acatalytic CA isoforms, CA VIII and CA X. CA XI is most abundantly expressed in brain, and may play a general role in the central nervous system.
CA11 has been shown to interact with RIPK1.
This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.